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The BIOFIRE System and Your Immune System The BIOFIRE System offers syndromic testing for infectious diseases, allowing healthcare professionals to choose the appropriate test first time. Patients benefit from faster diagnosis and more targeted treatment. Clinicians benefit from improved antibiotic stewardship. Labs improve efficiency and cost savings. The BioFire Pneumonia Plus Panel (PN panel) examines native sputum (including mini-BAL) and endotracheal lavage and bronchoalveolar slurries (including mini BAL) for 33 clinically significant pathogens and resistance genes to antimicrobials within one hour. Respiratory The burning of biomass (wood plants, trees and other organic material) produces gaseous pollutants as well as fine particles which negatively impact the respiratory system. Furthermore, the environmental issues caused by forest fires, like droughts, may be exacerbated by climate change, thereby increasing their negative impacts on the health of humans. In the United States wildfire smoke is associated with hospitalizations for respiratory illnesses like asthma, COPD, and lung cancer. Furthermore, this type of air pollution can be a risk factor for cardiovascular disease and is a significant contributing factor to the burden of disease in the most vulnerable populations, including people who are of lower socioeconomic status (SES). During the COVID-19 pandemic, a number of communities were exposed to unhealthy levels of air pollution due to wildfires. However the public health response to this environmental problem has been sporadic and mostly focused on communication regarding symptom management. This knowledge gap is alarming due to the fact that smoking cigarettes and other sources of poor quality air can cause health problems. Researchers are now looking at the best way to safeguard public's health in the event of future events of this kind. NIH invests in research on this critical public health issue through the BLUE CORAL and FIRE CORAL studies. For the first time, a prospective study will assess the long-term effects of exposure to smoke from wildfires or other sources. FIRE CORAL is looking for adult participants who have been hospitalized for COVID-19's index episode who have a fluency in English or Spanish and are not pregnant. The FIRE CORAL protocol includes a battery of tests conducted in-person, objectively measuring the pulmonary function test and lung imaging, as well as functional assessment. The lungs are particularly sensitive to the effects of smoke and other particles due to the fact that they can trigger or worsen chronic respiratory illnesses like emphysema or COPD and increase the risk of developing pneumonia. Smoke exposure can have adverse effects on health. To reduce or prevent these negative effects, avoid outdoor activities and wear the EPA “N95” mask. This mask is designed to trap small particles. Smoking cigarettes can cause irritation to the throat, eyes and nose. To minimize symptoms, drink lots of water and take medications that reduce inflammation, like corticosteroids. Bloodstream Bloodstream is the first line of defense against germs that enter your system. Dendritic cells, which are special cells, are like the fire department's call center; they collect the antigens (molecules that trigger an immune response) from germs that are invading your body and release proteins that trigger other white blood cells to fight them. The total number of white blood cells, differentials and band cells grew after firefighters' firefighting activities, compared to levels after strenuous exercise without fire-fighting. Skin Dermatologists were concerned that smoke and ash that resulted from the California wildfires could cause an adverse effect on the skin of those exposed to them. Maria Wei is a graduate student from University of California, Irvine. She studies how extreme wildfire pollution affects the skin. Her research was published on April 22 2012 in Scientific Reports. The study by Wei shows that temperature of the skin changes dependent on the amount of time the body is exposed. bio ethanol fire place takes upwards of two hours for the skin to reach its flash point, the place where it begins to burn and then turns to ash. It is important to avoid staying near a fire pit or campfire and wear protective clothing if you're outdoors in a humid or hot day. While it is important to be aware of the dangers of wildfire pollution, there is no way to stop forest fires from happening. Wei predicts that as climate change causes forests to burn more quickly, the number of people who suffer from wildfires will grow. This means that more people will have to wear hats, long sleeves, and thick moisturizers. It's also important to know that atopic dermatitis (itchy skin) that a lot of people suffer from can be exacerbated by air pollution from wildfires. She suggests that this is because smoke particles can block pores, which makes atopic dermatitis worse. Atopic dermatitis may also make people more sensitive towards UV light. This can be made worse by smoke from wildfires. This can cause people to be more likely to seek out tanning salons, and could cause people to tan less protection than they should. While a cold and fire facial may help reduce the effects of atopic dermatitis, it's not recommended for anyone with an open wound or rash on their face. This treatment is not recommended for patients with active acne, or if you're pregnant or nursing. The IS Clinical Fire & Ice Facial at Novuskin, Las Vegas' most prestigious membership MedSpa offers a thorough result-driven facial that bridges the gap between a light facial and a peel, without needing any downtime. It's designed to smooth the skin, reduce rosacea symptoms, decrease acne scarring, diminish wrinkles, and promote cell renewal. This is a great treatment to give your skin a glowing glow. Infections The human body is made up of a complex system of organs and tissue that work together to protect us against infection. Infections can be caused by microorganisms such as parasites, viruses, and bacteria that infect healthy cells, causing them to multiply uncontrollably. Your immune system could react by exhibiting symptoms of illness. The symptoms could range from a runny nose to a stomach that is upset as well as an increase in fever, swelling of lymph glands or an itchy scratch. The type of infection and the location can impact the symptoms. Infections can spread in a variety of ways but the most prevalent are transmitted from person to person by droppings that hang in the air after sneezing or coughing. Bacterial diseases like tuberculosis and strep throat meningococcal disease and Legionnaires' disease are spread in this manner, as do certain viral infections such as the common cold and influenza. Certain infections caused by bacteria, such as skin infections and sexually transmitted diseases (STIs) like gonorrhea or Chlamydia, can be transmitted through direct contact with infected tissue or mucous membranes, or through indirect contact with surfaces that are contaminated. Some bacterial infections are spread by insects such as ticks, fleas, or mosquitoes. The virus and the parasites are small enough to get into your bloodstream and infect your cells which can lead to serious diseases such as the common cold and AIDS. Fungi can cause a variety of skin ailments such as ringworm, athlete's foot, while some infect the lungs or nervous system, such as the rabies virus. The BioFire PN Panel employs our unique FilmArray technology to detect an extensive list of pathogens that are involved in upper respiratory infections in sputum or bronchoalveolar lavage fluid samples. The kit includes a reagent bag that includes all the chemistry required to perform reverse transcription as well as nested multiplex PCR detection in a single machine. It's a simple-to-use tool to help clinicians syndromicly identify and treat patients suffering from a variety of respiratory symptoms. This test has been granted an Emergency Use Authorization and is available through bioMerieux's CLIA moderate and high complexity labs.